| dc.description.abstract | Diabetes is a chronic, non-communicable disease that is becoming more popular in the modern world. Today, many drugs are manufactured to stabilize a person's blood sugar. Besides the conventional medication, the use of herbalism treatments for diseases have recently been gaining popularity. Herbal medicine is preferred, due to its supposedly fewer side effects and affordability. Many plant species have been found to be capable of stabilizing the blood sugar of diabetics, in which Momordicacharantia (MC), or bitter melon, has been demonstrated to have a high potential, thanks to one of its constituent compounds - charantin.
There are two types of MC in Vietnam: Chinese green and Indian green. The Chinese green species was chosen as the subject of study in this project due to its higher popularity. To collect the bioactive compounds in the MC, froth flotation was preferred, rather than chemical extractions. This method is typically used to remove hydrophobic bioactive compounds exist in the solution, bring them to the liquid/air interface. In this study, charantin was collected using froth flotation by air bubbles. It is sparingly soluble in water and other highly polar solvents. Therefore, charantin was selected as the substance capable of demonstrating the effectiveness of the flotation. The efficiency of the flotation were quantified and evaluated by TLC, FTIR, and phenol-sulfuric test for the determination of charantin in its glucoside form.
Keywords: charantin, momordica charantia, ultra-fined bubbles, flotation. | en_US |
