| dc.description.abstract | Eucalyptus citriodora essential oil is considered as a potential product and has been
attributed to various medicinal uses. Besides, triazine, a beneficial compound in
antibacterial treatment, was synthesized via nucleophilic addition of aldehyde and
amidine groups. In the study, Eucalyptus citriodora was extracted by the steaming
method to obtain Eucalyptus citriodora essential oil. GS-MS was used to analyze the
composition of essential oils. The result indicated that 83.17% of Citronellal was
found in their composition. Citronellal could react with amidine substrates at 90oC
for 1 hour in the presence of solvent DMSO and catalyst Na2CO3. Thin layer
chromatography and column chromatography were techniques that not only helped
to determine the presence of dihydro-1,3,5-triazine or triazine in the mobile phase
of hexane and ethyl acetate (8:2, v/v), but also purified the product after reaction.
Depending on the polarities of the product, dihydro-1,3,5-triazine was detected
after the purification process. The salt of amidine that contains strong deactivating
groups could be carried to a high yield of dihydro-1,3,5-triazine when it reacts with
aliphatic aldehyde. Moreover, NMR spectroscopy successfully confirms the structure
of dihydro-1,3,5-triazine. As a result, dihydro-1,3,5-triazine could be formed by the
reaction between Citronellal and amidine substrates, which could be applied in
biopharmaceuticals in the treatment of anti-bacterial properties. | en_US |
